Season the beef chunks generously with salt and pepper. Heat oil in a large Dutch oven over medium-high heat.
Working in batches, brown the meat on all sides, about 5 minutes per batch. Transfer to a plate.
Reduce heat to medium and add onions to the pot. Cook until softened, about 5 minutes.
Add garlic and all dry spices. Cook for 1 minute until fragrant.
Return meat to the pot. Add tomatoes, chipotle peppers, and beef broth.
Bring to a boil, then reduce heat and simmer, covered, for 2½ hours or until meat is tender.
Uncover and continue simmering for 30 minutes to thicken the sauce.
Preheat oven to 375°F. Grease a 9-inch cast-iron skillet or baking pan.
Whisk together cornmeal, flour, baking powder, baking soda, and salt.
In another bowl, beat eggs, buttermilk, honey, and melted butter.
Combine wet and dry ingredients, stirring just until mixed.
Pour into prepared pan and bake for 20-25 minutes until golden brown.